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Disease  area

Its expression pattern is close to the natural physiological state, which can more accurately simulate the pathological mechanism of AD in the brain

Advantage

1

High efficiency, short cycle, and low cost

Advantage

2

Models of Neurological Diseases

1.Models of Neurological Diseases

Tau protein with high phosphorylation similar to humans

Advantage

3

The pathological phenotype is obvious and unique

Advantage

4

In addition, the blood volume and cerebrospinal fluid volume of rats are much larger than those of mice, making it more suitable for continuous multiple sampling, which is beneficial for the drug development process.

Advantage

5

2.Stroke model

3.PD model

4.Spinal cord injury model

5.AD model

6.Depression model

7.Epilepsy model Ischemic infarction model/sham operation

8.Intracerebral haemorrhage model

9.Subarachnoid haemorrhage model

10.A model of ischaemic-hypoxic brain injury in neonatal mice

11.Spinal cord transection model